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Audience

Audience: Intended for everyone interested in Neurochemistry, particularly undergraduate and graduate life science students, medical students, and nursing students.

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Table of Contents

I. Neurocellular Anatomy

Neuron: Axon | Dendrite

Axonal Transport and Growth: Axoplasmic transport | Kinesin | Dynein | Myosin | Growth cone | Axon guidance

Synapse: Synaptic Vesicles | Exocytosis | Endocytosis | Synaptic plasticity | SNARE | Synaptobrevin | Synapsin | NSF

Glial cell: Astrocyte | Oligodendrocyte | Schwann cell | Myelin | Nodes of Ranvier | Multiple sclerosis

Cytoskeleton: Actin | Intermediate filament | Microtubule

II. Membranes And Transport

Membrane Structure: Fluid mosaic model | Detailed Structure

Lipids: Fatty acid | Fatty acid degradation | Fatty acid synthesis | Triglyceride | Waxes | Lipoprotein | Cholesterol

Membrane Components: Phospholipids | Sphingomyelin | Glycolipid | Glycocalix | Cholesterol | Antigen

Movement of Molecules: Diffusion | Osmosis | Electrochemical gradient

Passive transport: Facilitated diffusion | Ion channel

Active transport: ATP-Dependent Na/K Pump | V-ATPase | Proton pump | Electron transport | Antiporter | Symporter

Blood-brain barrier: Tight junction | Cerebrospinal fluid

III. Ion Channels

Channels: Ion channel | Gap junction

Voltage-gated: Potassium channel | Sodium channel | BK channel | Inward-rectifier potassium ion channel | Resting channels | Calcium channel

Ligand-gated: NMDA receptor | AMPA receptor | Kainate receptor | Nicotinic acetylcholine receptor | Glycine receptor | GABA A receptor | GABA B receptor | GABA C receptor

Other ion channels: Cyclic nucleotide-gated | Stretch-activated | G-protein-gated | Light-gated

IV. Extracellular Signaling

Acetylcholine: Degradation by acetylcholinesterase | Receptors Overview | Nicotinic Receptors | Muscarinic Receptors | Muscarinic receptor agonist

Catecholamines: Epinephrine | Norepinephrine | Norepinephrine transporter | Dopamine | Dopamine transporter | Levodopa | Catecholamines breakdown | Adrenergic receptor | Dopamine receptor

Major dopamine pathways: Mesocortical pathway | Nigrostriatal pathway | Mesolimbic pathway | Tuberoinfundibular pathway

Serotonin: Serotonin transporter | Selective serotonin reuptake inhibitor | Receptors

Histamine: H1 receptor | H2 receptor | H3 receptor | H4 receptors | Antihistamine drugs

Glutamate: NMDA receptor | AMPA receptor | Kainate receptor | Glutamate transporter

GABA and Glycine: GABA | GABA A receptor | GABA B receptor | GABA C receptor | Glycine | Glycine Receptor | Inhibitory postsynaptic potential

Other Extracellular Signaling Molecules: Purines | Nitric oxide

Neuropeptides: Endorphin | Opioid receptor | Neuropeptide Y | Substance P | Neurokinin 1 | Cholecystokinin | Cholecystokinin receptor

Growth Factors: Granulocyte colony-stimulating factor | Nerve growth factor | Neurotrophin | Platelet-derived growth factor | Erythropoietin | Thrombopoietin | Myostatin | Basic fibroblast growth factor

Cell Adhesion: Families of cell adhesion molecules | Immunoglobulin Family | Integrins | Cadherin | Selectin

V. Intracellular Signalling

Intracellular signalling: Signal Amplification | Second messenger | Nuclear receptors | Calcium

Protein phosphorylation: Kinases | Serine/threonine-specific protein kinases | Phosphorylase kinase | Protein kinase A | Protein kinase C | Ca2+/calmodulin-dependent protein kinases | MAP kinases | Mos/Raf kinases | Tyrosine-specific protein kinases | Histidine-specific protein kinases | Phosphatase | Calmodulin

G-Protein: G-protein-coupled receptors | GTPase

Phosphoinositides: Phosphatidylinositol | Phosphoinositide 3-kinase | Phosphatidylinositol (3,4)-bisphosphate | Phosphatidylinositol (3,5)-bisphosphate | Phosphatidylinositol (3,4,5)-trisphosphate

Lipophilic molecules: Diacylglycerol | Phospholipase | Inositol triphosphate | Prostaglandins | Ceramide | Cyclooxygenases | Eicosanoids

Cyclic Nucleotides: cAMP | Adenylate cyclase | cAMP-dependent protein kinase | cGMP | Guanylate cyclase | Phosphodiesterase

Techniques: CT | MRI | fMRI | PET | SPECT

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